Which salivary gland tumor is characterized histologically by the presence of 'intermediate cells'?
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Answer: B. Mucoepidermoid carcinoma
Explanation
Mucoepidermoid carcinomas feature a distinct mixture of three cell types. Intermediate cells serve as a hallmark histological finding for diagnosis. Mucous cells and epidermoid cells complete the characteristic cellular triad. This malignancy represents the most common malignant salivary gland tumor. Tumors can arise within major or minor salivary gland tissues. Histological grading dictates the clinical aggressiveness and metastatic potential.
Surgical excision with appropriate margins is the primary treatment modality. Pathologists rely on intermediate cells to differentiate this from other tumors. Postoperative radiation therapy may be indicated for high-grade malignant tumors. Adenoid cystic carcinomas exhibit cribriform patterns without intermediate cells. Pleomorphic adenomas contain epithelial and stromal elements without intermediate cells. Warthin tumors consist of oncocytic cells and lymphoid stroma.
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