The medication of choice for treating infections driven by non-penicillinase-producing staphylococci is___________?
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Answer: C. Penicilling G
Explanation
Penicillin G is exceptionally potent against non-penicillinase-producing staphylococcal strains. Sensitive bacteria lack the protective beta-lactamase enzymes that hydrolyze the antibiotic. The drug disrupts bacterial cell wall synthesis effectively in these susceptible populations. Penicillin G represents the original natural antimicrobial isolated from penicillium molds. Staphylococci historically developed widespread resistance via plasmid-mediated penicillinase production. Non-resistant isolates remain exquisitely vulnerable to standard penicillin therapy.
Antimicrobial stewardship relies on identifying specific bacterial susceptibilities before treatment. Using narrow-spectrum agents prevents the development of multi-drug resistant superinfections. Severe systemic infections require parenteral administration to maintain high serum levels. Option A ampicillin is a broad-spectrum penicillin often reserved for gram-negative bacilli. Option B erythromycin is a macrolide alternative used for penicillin-allergic patients. Option D methicillin is a semi-synthetic agent designed for penicillinase producers.
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Answer: C. Iodine
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