Histological detection of hemosiderin granules is characteristic of_____________?
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Answer: C. Peripheral giant cell granuloma
Explanation
Peripheral giant cell granulomas contain abundant extravasated red blood cells. Breakdown of these erythrocytes releases iron stored as hemosiderin granules. Histological detection of hemosiderin confirms previous hemorrhage within the lesion. This reactive gingival lesion arises from periodontal ligament or periosteum. Multinucleated giant cells proliferate within a vascular fibrous connective tissue stroma. Lesions present as red or purplish nodules on the gingival mucosa.
Surgical excision down to the underlying bone prevents recurrence. Trauma or local irritation typically triggers the reactive growth of tissue. Pathological examination confirms the diagnosis by revealing giant cells. Fibromas consist of dense collagen without significant hemorrhage or giant cells. Pregnancy tumors are pyogenic granulomas showing high vascularity without hemosiderin predominance. Papillomas are benign epithelial proliferations lacking internal giant cells.
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