Granular cell myoblastoma of the tongue is described as____________?
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Answer: A. Benign tumor
Explanation
Granular cell tumor of the tongue is classified strictly as a benign soft tissue neoplasm. It originates from Schwann cells of the peripheral nervous system rather than primitive myoblasts. Histologically, it exhibits large polygonal cells filled with abundant eosinophilic granules and benign behavior. Granular cell tumors commonly present as painless, firm, sessile submucosal nodules on the dorsal tongue. The overlying epithelium frequently demonstrates pseudoepitheliomatous hyperplasia, which can mimic squamous cell carcinoma. Surgical excision is curative, and recurrence is extremely rare following complete removal of the lesion.
Oral pathologists carefully evaluate biopsy specimens to ensure pseudoepitheliomatous hyperplasia is not mistaken for malignancy. Patients usually notice a slow-growing asymptomatic lump that has persisted for months or even years. Accurate diagnosis ensures patients receive conservative surgical management instead of aggressive oncological treatments. Malignant tumors of the tongue exhibit aggressive local invasion, cellular atypia, and regional lymph node metastasis. Lymphatic enlargement represents a reactive or neoplastic response of immune tissues rather than a granular cell tumor. Developmental anomalies are congenital structural variations, whereas granular cell tumors are true acquired neoplasms.
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