A 3-year-old patient exhibits widespread vesicles on the lips, tongue, and oral mucosa. After 2 to 4 days, these vesicles rupture, leading to pseudomembrane formation alongside dermal lesions. What is the expected diagnosis?
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Answer: B. EM
Explanation
Erythema multiforme is an acute immune-mediated condition characterized by widespread oral bullae. Rupturing vesicles lead to painful pseudomembrane formation alongside classic dermal target skin lesions. The disease typically has an abrupt onset with mucosal erosions and characteristic crusting lip lesions. This hypersensitivity reaction is frequently triggered by viral infections like herpes simplex or certain drugs. Target lesions feature concentric rings of color change with central blistering on the extremities. Mucosal involvement can range from mild oral blistering to severe erosions affecting multiple sites.
Managing erythema multiforme involves identifying and eliminating the underlying trigger, such as a herpes outbreak. Topical and systemic corticosteroids are frequently prescribed to control the acute inflammatory immune response. Maintaining oral hydration and nutrition is challenging due to the severe pain caused by mucosal ulcerations. Herpetic stomatitis presents with clustered small vesicles that rupture, but lacks the generalized target skin lesions. ANUG is a localized necrotizing periodontal infection characterized by punched-out papillae and foul odor. Stevens-Johnson syndrome is a much more severe form of erythema multiforme involving extensive skin detachment.
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