A 20-year-old patient presents with multiple jaw swellings. Clinical examination uncovers several missing teeth and multiple hard jaw swellings, while a panoramic radiograph shows numerous radiopaque lesions, impacted teeth, and supernumerary teeth in both jaws, pointing toward Gardner's syndrome. This condition is best described as______________?
Show answer Hide answer
Answer: A. Autosomal dominant disease
Explanation
Gardner's syndrome is classified as an autosomal dominant genetic disorder affecting multiple organ systems. Affected individuals inherit a mutated APC gene that predisposes them to numerous characteristic manifestations. Every child of an affected parent carries a fifty percent risk of inheriting this genetic condition. Gardner's syndrome is a phenotypic variant of familial adenomatous polyposis characterized by intestinal polyps. Dental findings often include multiple impacted teeth, osteomas of the jaws, and numerous supernumerary teeth. Skin cysts and soft tissue tumors frequently accompany the skeletal and gastrointestinal abnormalities.
Early dental screening can lead to the incidental early diagnosis of potentially fatal intestinal polyposis. Gastroenterologists monitor patients with this syndrome closely due to the extremely high risk of colon cancer. Genetic counseling is essential for affected families to understand inheritance patterns and screening protocols. Autosomal recessive disorders require two mutated gene copies, which does not match Gardner's syndrome. X-linked inheritance patterns involve genes located on the sex chromosomes, unlike this condition. Classifying it as a syndrome of unknown cause is false because the exact genetic mutation is well known.
Related questions
Q1. Which lingual papillae undergo complete keratinization______________?
Show answer Hide answer
Answer: B. Filiform
Filiform papillae undergo complete keratinization, which creates their distinctively rough and abrasive texture. This complete surface keratinization allows them to efficiently process food during active chewing movement...
Q2. The periodontal ligament reaches its minimum width at______________?
Show answer Hide answer
Answer: C. Fulcrum of rotation
The periodontal ligament is narrowest around the fulcrum of rotation located in the middle third of the root. During physiological tooth movement, the tooth pivots around this narrow fulcrum zone within the alveolar sock...
Q3. A 3-year-old patient presents with painless, progressive bilateral facial swellings. The provisional diagnosis is______________?
Show answer Hide answer
Answer: A. Cherubism
Cherubism is a genetic condition featuring painless, bilateral facial swellings. It presents characteristically with symmetric expansile jaw lesions in children. This inherited disorder causes a cherubic facial appearanc...
Q4. A 36-year-old man presents with an asymptomatic swelling in the body of the mandible, with radiographs demonstrating a radiolucency containing radiopaque flecks. He is suffering from:
Show answer Hide answer
Answer: B. Calcifying epithelial odontogenic tumor (CEOT)
Calcifying epithelial odontogenic tumors are benign intraosseous neoplasms presenting as radiolucencies with radiopaque flecks. These calcified structures, known as Pindborg tumor rings, appear as scattered radiopaque fl...
Q5. A 3 year old child has a fever of 102 degree F; coupled with an upper respiratory tract infection, showing discrete vesicles and ulcers on the soft plate and pharynx. The most probable diagnosis is _____________?
Show answer Hide answer
Answer: A. Herpangina
Herpangina is a common childhood viral infection caused primarily by enteroviruses like coxsackievirus. Clinical presentation includes moderate to high fever accompanied by characteristic vesicular oral mucosal lesions....
Q6. A 15-year-old boy presents with a fast-growing mandibular swelling accompanied by intermittent pain following trauma. Radiographs show new subperiosteal bone formation with an onion-skin pattern, alongside lip paresthesia and an elevated white blood cell count. Based on these findings, what condition should be included in the provisional diagnosis_________________?
Show answer Hide answer
Answer: D. Ewing’s sarcoma
Ewing sarcoma often presents with rapid bone swelling and pain in youth. Radiographs demonstrate characteristic subperiosteal bone formation with onion-skin patterns. Associated symptoms include lip paresthesia and eleva...