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Question no. 5178

The volume of cells eliminated in healthy adult humans via programmed apoptosis is ________ ?

Select your answer for: The volume of cells eliminated in healthy adult humans via programmed apoptosis is ________ ?
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Answer: B. 50 to 70 billion cells

Explanation

Programmed cell death, or apoptosis, is a regulated process that removes damaged or unneeded cells safely. In a healthy adult human, billions of cells undergo this controlled turnover daily to maintain tissue homeostasis. Scientific estimates consistently place this routine cellular elimination between 50 to 70 billion cells per day. Apoptosis involves caspase enzyme activation that systematically disassembles cellular components without causing inflammation. This process balances cellular proliferation to keep organ sizes stable in adult human tissues. Phagocytic cells quickly engulf and clear apoptotic bodies before any leakage of intracellular contents occurs.

Defects in apoptotic pathways can lead to runaway cell survival, resulting in the formation of cancerous tumors. Conversely, excessive apoptosis contributes to neurodegenerative disorders like Alzheimer's and Parkinson's disease. Understanding programmed cell death helps researchers design therapies that trigger cancer cell self-destruction. 20 to 35 billion cells underestimates the high daily rate of natural apoptotic turnover in human adults. 10 to 20 billion cells is far too low compared to established physiological cell replacement estimates. 15 to 25 billion cells fails to reflect the extensive daily cellular recycling occurring in adult tissues.

Subject
Biology
Category
Biology
Topic
—
Difficulty
medium

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